It all depends on one's style of coyote hunting. I could definitely make that rifle work if it were chambered in a 22-250 or 243. However the barrel twist would have to be for heavier bullets and rifle manufacturer's almost never do that. That stock design is perfect for longer shots particularly from a prone position. From a sitting position, for close shots, I imagine it will be a little cumbersome, but probably no more than most AR-15's. From prone though, that stock combined with the medium weight barrel, should be flat out deadly between 300 to 500 or more yards, depending on the shooters ability, and the accuracy of the rifle. In Mossberg's defense they are not touting it as a "predator" rifle. It's titled as a varmint rifle and it should be perfect for that, but it certainly could do double duty. If I lived were most my shots were under 100 yards I would not be very interested in that rifle. However, I live in wide open prairie country as do a lot of mid western hunters. Many shots are 150 to 300 yards or more. That rifle would definitely be useful if they offer it in more than just .223.