Originally Posted By: bigtommySe mn average shot is 200 to 300 with possibility of 400
OK, then I'd suggest 2 options. Both of which I own and use in Minnesota.
.243 with 50-60 grain bullets. I have a Tikka and it's awesome with these loads and it can also fire a 90 grain BT with the same level of accuracy. A tremendously versatile rifle considering the price.
or...
.22-250 - Again, I have a Tikka. Of all your options, the .22-250 is the king of the reach-out-and-touch-em rifles. It's freaky-flat to the point where it's unbelieveable. Even with the same weight bullets, my 250 is significantly flatter than the 243 at all ranges 300 and beyond.
Fur damage? Everything depends on where you hit them and at what range with these rifles. Obviously, there is a compromise that you're going to have to make here, especially if you keep the requirement for it to serve double duty as a deer rifle.
Some might suggest tricks like using FMJ bullets. I'm not sure how I feel about these in areas that have the people population density of SE MN. I'm super careful about where the bullet might end up.
Grouse