I'll agree with ruger300 on calibers. I've got a couple of 243's that probably would be my top choice, but if they run the hunting concurrent with big game season then my 280 Remington or the 8mm Rem mag will be with me for deer or elk.
Though a wolf is quit a bit bigger than a coyote as ruger says "a wolf is just a bigger varmint".
One thing for sure that should make a dandy hide to put on the wall. In fact I'd kinda like to have all the walls covered. Perhaps that would leave me an elk to shoot with that old 8mm mag.