Type your info into a ballistics calculator and look at your trajectory. You will have a near and far zero. With my one thermal without built in ballistics on a 22-250 , my near and far are 50 yards and 250 yards. Anything out to 300 is a dead hold on a coyote. Sight in at 50 yards or whatever your near zero is , is a heck of a lot easier than trying to get zeroed in at distance. Scope height is an important number in your calculator btw and will be a big factor in your zero distance. Mine sits at 2.5” above the bore.
Last time I swapped the scope from a rimfire back to the 22-250 I shot once at 50 yards , adjusted and shot again and was on the money. One more shot to confirm and off hunting I went. One coyote dropped that night was at 277 yards. Really can’t get much easier than that.