You are going to find out that the 17HMR is the most hated cartridge ever developed, if you listen to most of the posters on here. Is it the best choice for coyote hunting....no. Will it kill a coyote....yes. I used a 17HMR for my farm gun for several years, carrying it in the truck, on the 4-wheeler, and on the tractor. I probably shot and killed a dozen coyotes with it. All were one shot kills at ranges of a 100 yards or less. Most of the posters who will say not to use it, have never used one. I don't use the 17HMR anymore to hunt with, but if it's all I had, I would use it and never think twice about it.